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Mechanistic Insights into the Activation of Oncogenic Forms of EGF Receptor
Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly activated by mutation in non-small cell lung cancer. The mechanism of this oncogenic activation is incompletely understood but, in contrast to the WT EGFR, is proposed to be independent of kinase domain dimerizati...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230693/ https://ncbi.nlm.nih.gov/pubmed/22101934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2168 |
| Tagiau: |
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