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Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death
The present studies were initiated to determine in greater molecular detail the regulation of CHK1 inhibitor lethality in transfected and infected breast cancer cells and using genetic models of transformed fibrobalsts. Multiple MEK1/2 inhibitors (PD184352, AZD6244 [ARRY-142886]) interacted with mul...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230482/ https://ncbi.nlm.nih.gov/pubmed/21642769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.3.16218 |
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