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IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors

Solid tumors are complex masses with a local microenvironment, or stroma, that supports tumor growth and progression. Among the diverse tumor-supporting stromal cells is a heterogeneous population of myeloid-derived cells. These cells are alternatively activated and contribute to the immunosuppressi...

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Main Authors: Kerkar, Sid P., Goldszmid, Romina S., Muranski, Pawel, Chinnasamy, Dhanalakshmi, Yu, Zhiya, Reger, Robert N., Leonardi, Anthony J., Morgan, Richard A., Wang, Ena, Marincola, Francesco M., Trinchieri, Giorgio, Rosenberg, Steven A., Restifo, Nicholas P.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226001/
https://ncbi.nlm.nih.gov/pubmed/22056381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58814
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