IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors

Solid tumors are complex masses with a local microenvironment, or stroma, that supports tumor growth and progression. Among the diverse tumor-supporting stromal cells is a heterogeneous population of myeloid-derived cells. These cells are alternatively activated and contribute to the immunosuppressi...

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Main Authors: Kerkar, Sid P., Goldszmid, Romina S., Muranski, Pawel, Chinnasamy, Dhanalakshmi, Yu, Zhiya, Reger, Robert N., Leonardi, Anthony J., Morgan, Richard A., Wang, Ena, Marincola, Francesco M., Trinchieri, Giorgio, Rosenberg, Steven A., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226001/
https://ncbi.nlm.nih.gov/pubmed/22056381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58814
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