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Antibacterial and Antitubercular Activity of Fosmidomycin, FR900098, and their Lipophilic Analogs
The nonmevalonate pathway (NMP) of isoprene biosynthesis is an exciting new route toward novel antibiotic development. Inhibitors against several enzymes in this pathway are currently under examination. A significant liability of many of these agents is poor cell penetration. To overcome and improve...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215086/ https://ncbi.nlm.nih.gov/pubmed/22024034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.09.123 |
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