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Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents
The natural product engelhardione is an underexplored chemotype for developing novel treatments for bacterial infections; we therefore explored this natural product scaffold for chemical diversification and structure-activity relationship studies. Macrocyclic engelhardione and structural regioisomer...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696040/ https://ncbi.nlm.nih.gov/pubmed/23549356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2013.21 |
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