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Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives
[Image: see text] A series of novel chalcone and thiol-Michael addition analogues was synthesized and tested against Mycobacterium tuberculosis and other clinically significant bacterial pathogens. Previously reported chalcone-like antibacterials (1a–c and 2) were used as a training set to generate...
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| 出版年: | ACS Omega |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2018
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6312637/ https://ncbi.nlm.nih.gov/pubmed/30613820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03174 |
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