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Potentiation of the Fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida()

A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the F...

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Publicat a:Medchemcomm
Autors principals: Stephens, Matthew D., Yodsanit, Nisakorn, Melander, Christian
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279706/
https://ncbi.nlm.nih.gov/pubmed/28154750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6MD00365F
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