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Evaluation of Ethyl N-(2-Phenethyl) Carbamate Analogues as Biofilm Inhibitors of Methicillin Resistant Staphylococcus aureus

A small molecule library consisting of 45 compounds was synthesized based on the bacterial metabolite ethyl N-(2-phenethyl) carbamate. Screening of the compounds revealed a potent analogue capabale of inhibiting several strains of Methicillin Resistant S. aureus biofilms with low to moderate micromo...

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Pubblicato in:Org Biomol Chem
Autori principali: Stephens, Matthew D., Yodsanit, Nisakorn, Melander, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942382/
https://ncbi.nlm.nih.gov/pubmed/27341658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00706f
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