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N-Benzylanilines as Fatty Acid Synthesis Inhibitors against Biofilm-related Methicillin-resistant Staphylococcus aureus

[Image: see text] Bacterial fatty acid synthase system is a well validated target for the development of novel antimicrobial agents. This study reports the synthesis of Schiff bases and their reductive N-benzylanilines. Most N-benzylanilines were active against Gram-positive bacteria, among which co...

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Publicado en:ACS Med Chem Lett
Autores principales: Zhang, Jing, Huang, Hao, Zhou, Xueting, Xu, Yingying, Chen, Baochun, Tang, Wenjian, Xu, Kehan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2019
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421535/
https://ncbi.nlm.nih.gov/pubmed/30891135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00612
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