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Crystallographic and kinetic evidence of allostery in a trypsin-like protease()

Protein allostery is based on the existence of multiple conformations in equilibrium linked to distinct functional properties. Although evidence of allosteric transitions is relatively easy to identify by functional studies, structural detection of a pre-existing equilibrium between alternative conf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Niu, Weiling, Chen, Zhiwei, Gandhi, Prafull S., Vogt, Austin D., Pozzi, Nicola, Pelc, Leslie A., Zapata, Fatima, Di Cera, Enrico
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214630/
https://ncbi.nlm.nih.gov/pubmed/21707111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200878c
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