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Crystallographic and kinetic evidence of allostery in a trypsin-like protease()
Protein allostery is based on the existence of multiple conformations in equilibrium linked to distinct functional properties. Although evidence of allosteric transitions is relatively easy to identify by functional studies, structural detection of a pre-existing equilibrium between alternative conf...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214630/ https://ncbi.nlm.nih.gov/pubmed/21707111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200878c |
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