Crystal Structure of Thrombin Bound to the Uncleaved Extracellular Fragment of PAR1

Por Gandhi, Prafull S., Chen, Zhiwei, Di Cera, Enrico
Publicado em 2010

Structural identification of the pathway of long-range communication in an allosteric enzyme

Por Gandhi, Prafull S., Chen, Zhiwei, Mathews, F. Scott, Di Cera, Enrico
Publicado em 2008

Stabilization of the E* Form Turns Thrombin into an Anticoagulant

Por Bah, Alaji, Carrell, Christopher J., Chen, Zhiwei, Gandhi, Prafull S., Di Cera, Enrico
Publicado em 2009

Engineering Thrombin for Selective Specificity toward Protein C and PAR1

Por Marino, Francesca, Pelc, Leslie A., Vogt, Austin, Gandhi, Prafull S., Di Cera, Enrico
Publicado em 2010

Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A

Por Gandhi, Prafull S., Page, Michael J., Chen, Zhiwei, Bush-Pelc, Leslie, Di Cera, Enrico
Publicado em 2009

Mutant N143P Reveals How Na(+) Activates Thrombin

Por Niu, Weiling, Chen, Zhiwei, Bush-Pelc, Leslie A., Bah, Alaji, Gandhi, Prafull S., Di Cera, Enrico
Publicado em 2009

Crystallographic and kinetic evidence of allostery in a trypsin-like protease()

Por Niu, Weiling, Chen, Zhiwei, Gandhi, Prafull S., Vogt, Austin D., Pozzi, Nicola, Pelc, Leslie A., Zapata, Fatima, Di Cera, Enrico
Publicado em 2011

Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity

Por Sorensen, Anders B., Madsen, Jesper J., Svensson, L. Anders, Pedersen, Anette A., Østergaard, Henrik, Overgaard, Michael T., Olsen, Ole H., Gandhi, Prafull S.
Publicado no J Biol Chem (2016)

Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor

Por Hennen, Stephanie, Kodra, János T., Soroka, Vladyslav, Krogh, Berit O., Wu, Xiaoai, Kaastrup, Peter, Ørskov, Cathrine, Rønn, Sif G., Schluckebier, Gerd, Barbateskovic, Silvia, Gandhi, Prafull S., Reedtz-Runge, Steffen
Publicado no Sci Rep (2016)

Engineering of a membrane-triggered activity switch in coagulation factor VIIa

Por Nielsen, Anders L., Sorensen, Anders B., Holmberg, Heidi L., Gandhi, Prafull S., Karlsson, Johan, Buchardt, Jens, Lamberth, Kasper, Kjelgaard-Hansen, Mads, Ley, Carsten Dan, Sørensen, Brit B., Ruf, Wolfram, Olsen, Ole H., Østergaard, Henrik
Publicado no Proc Natl Acad Sci U S A (2017)