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Crystal Structure of Thrombin Bound to the Uncleaved Extracellular Fragment of PAR1
Abundant structural information exists on how thrombin recognizes ligands at the active site or at exosites separate from the active site region, but remarkably little is known about how thrombin recognizes substrates that bridge both the active site and exosite I. The case of the protease-activated...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865304/ https://ncbi.nlm.nih.gov/pubmed/20236938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115337 |
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