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Autoactivation of Thrombin Precursors

Trypsin-like proteases are synthesized as inactive zymogens and convert to the mature form upon activation by specific enzymes, often assisted by cofactors. Central to this paradigm is that the zymogen does not convert spontaneously to the mature enzyme, which in turn does not feed back to activate...

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Detalhes bibliográficos
Main Authors: Pozzi, Nicola, Chen, Zhiwei, Zapata, Fatima, Niu, Weiling, Barranco-Medina, Sergio, Pelc, Leslie A., Di Cera, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630838/
https://ncbi.nlm.nih.gov/pubmed/23467412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.451542
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