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Histone H4 Promotes Prothrombin Autoactivation

Recent studies have documented the ability of prothrombin to spontaneously convert to the mature protease thrombin when Arg-320 becomes exposed to solvent for proteolytic attack upon mutation of residues in the activation domain. Whether prothrombin autoactivation occurs in the wild-type under condi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Barranco-Medina, Sergio, Pozzi, Nicola, Vogt, Austin D., Di Cera, Enrico
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861626/
https://ncbi.nlm.nih.gov/pubmed/24178300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509786
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