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Histone H4 Promotes Prothrombin Autoactivation
Recent studies have documented the ability of prothrombin to spontaneously convert to the mature protease thrombin when Arg-320 becomes exposed to solvent for proteolytic attack upon mutation of residues in the activation domain. Whether prothrombin autoactivation occurs in the wild-type under condi...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861626/ https://ncbi.nlm.nih.gov/pubmed/24178300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509786 |
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