Wird geladen...
Why Ser and not Thr brokers catalysis in the trypsin fold()
Although Thr is equally represented as Ser in the human genome and is as good a nucleophile, it is never found in the active site of the large family of trypsin-like proteases that utilize the Asp/His/Ser triad. The molecular basis of the preference of Ser over Thr in the trypsin fold was investigat...
Gespeichert in:
| Veröffentlicht in: | Biochemistry |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342846/ https://ncbi.nlm.nih.gov/pubmed/25664608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00014 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|