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Essential role of conformational selection in ligand binding
Two competing and mutually exclusive mechanisms of ligand recognition – conformational selection and induced fit - have dominated our interpretation of ligand binding in biological macromolecules for almost six decades. Conformational selection posits the pre-existence of multiple conformations of t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945038/ https://ncbi.nlm.nih.gov/pubmed/24113284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2013.09.003 |
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