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Conformational selection is a dominant mechanism of ligand binding

Molecular recognition in biological macromolecules is achieved by binding interactions coupled to conformational transitions that precede or follow the binding step, two limiting mechanisms known as conformational selection and induced fit, respectively. Sorting out the contribution of these mechani...

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Detalhes bibliográficos
Main Authors: Vogt, Austin D., Di Cera, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791601/
https://ncbi.nlm.nih.gov/pubmed/23947609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400929b
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