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Allostery in trypsin-like proteases suggests new therapeutic strategies
Trypsin-like proteases are a large family of enzymes responsible for digestion, blood coagulation, fibrinolysis, development, fertilization, apoptosis and immunity. A current paradigm posits that the irreversible transition from an inactive zymogen to the active protease form enables productive inte...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191250/ https://ncbi.nlm.nih.gov/pubmed/21726912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2011.06.001 |
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