Φορτώνει......
CIIA functions as a molecular switch for the Rac1-specific GEF activity of SOS1
Son of sevenless 1 (SOS1) is a dual guanine nucleotide exchange factor (GEF) that activates the guanosine triphosphatases Rac1 and Ras, which mediate signaling initiated by peptide growth factors. In this paper, we show that CIIA is a new binding partner of SOS1. CIIA promoted the SOS1–Rac1 interact...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Rockefeller University Press
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206349/ https://ncbi.nlm.nih.gov/pubmed/22042618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106138 |
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