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CIIA prevents SOD1(G93A)-induced cytotoxicity by blocking ASK1-mediated signaling
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease with higher selectivity in degeneration of motor neurons. However, the molecular mechanism by which the ALS-linked mutants of human superoxide dismutase 1 (SOD1) gene induce neurotoxicity remains obscure yet. Here, we sh...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071562/ https://ncbi.nlm.nih.gov/pubmed/25018698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00179 |
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