Neuromuscular effects of G93A-SOD1 expression in zebrafish

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal disorder involving the degeneration and loss of motor neurons. The mechanisms of motor neuron loss in ALS are unknown and there are no effective treatments. Defects in the distal axon and at the neuromuscular junction are early events in the...

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Autores principales: Sakowski, Stacey A, Lunn, J Simon, Busta, Angela S, Oh, Sang Su, Zamora-Berridi, Grettel, Palmer, Madeline, Rosenberg, Andrew A, Philip, Stephen G, Dowling, James J, Feldman, Eva L
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506515/
https://ncbi.nlm.nih.gov/pubmed/22938571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-44
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