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Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration

Amyotrophic Lateral Sclerosis (ALS) is an adult-onset neurodegenerative disorder characterized by selective loss of motor neurons (MNs). Twenty percent of familial ALS cases are associated with mutations in Cu(2+)/Zn(2+) superoxide dismutase (SOD1). To specifically understand the cellular mechanisms...

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Detalhes bibliográficos
Main Authors: Lunn, J. Simon, Sakowski, Stacey A., Kim, Bhumsoo, Rosenberg, Andrew A., Feldman, Eva L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853013/
https://ncbi.nlm.nih.gov/pubmed/19672955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20747
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