Influence of Methylene Blue on Microglia-Induced Inflammation and Motor Neuron Degeneration in the SOD1(G93A) Model for ALS

Mutations in SOD1 cause hereditary variants of the fatal motor neuron disease amyotrophic lateral sclerosis (ALS). Pathophysiology of the disease is non-cell-autonomous, with toxicity deriving also from glia. In particular, microglia contribute to disease progression. Methylene blue (MB) inhibits th...

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Detaylı Bibliyografya
Asıl Yazarlar: Dibaj, Payam, Zschüntzsch, Jana, Steffens, Heinz, Scheffel, Jörg, Göricke, Bettina, Weishaupt, Jochen H., Le Meur, Karim, Kirchhoff, Frank, Hanisch, Uwe-Karsten, Schomburg, Eike D., Neusch, Clemens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428282/
https://ncbi.nlm.nih.gov/pubmed/22952827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043963
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