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Deficiency in the ALS2 gene does not affect the motor neuron degeneration in SOD1(G93A) transgenic mice

Dysfunction of the ALS2 gene has been linked to one form of juvenile onset autosomal recessive amyotrophic lateral sclerosis (ALS). Previous in vitro studies suggest that over-expression of ALS2 protects cells from mutant Cu/Zn superoxide dismutase (SOD1)-induced cytotoxicity. To test whether ALS2 p...

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Detalhes bibliográficos
Main Authors: Lin, Xian, Shim, Hoon, Cai, Huaibin
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423343/
https://ncbi.nlm.nih.gov/pubmed/16973244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2006.07.014
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