CIIA functions as a molecular switch for the Rac1-specific GEF activity of SOS1

Son of sevenless 1 (SOS1) is a dual guanine nucleotide exchange factor (GEF) that activates the guanosine triphosphatases Rac1 and Ras, which mediate signaling initiated by peptide growth factors. In this paper, we show that CIIA is a new binding partner of SOS1. CIIA promoted the SOS1–Rac1 interact...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hwang, Hyun Sub, Hwang, Sang Gil, Cho, Jun-Ho, Chae, Ji Soo, Yoon, Kyoung Wan, Cho, Ssang-Goo, Choi, Eui-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206349/
https://ncbi.nlm.nih.gov/pubmed/22042618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106138
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados