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An important role for Akt3 in platelet activation and thrombosis
The Akt family of serine/threonine kinases includes Akt1, Akt2, and Akt3 isoforms. Prior studies have reported that Akt1 and Akt2, but not Akt3, are expressed in platelets. Here, we show that Akt3 is expressed in substantial amounts in platelets. Akt3(−/−) mouse platelets selectively exhibit impaire...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204738/ https://ncbi.nlm.nih.gov/pubmed/21821713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-323204 |
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