The role of Akt in the signaling pathway of the glycoprotein Ib-IX–induced platelet activation

The platelet von Willebrand factor (vWF) receptor, glycoprotein Ib-IX (GPIb-IX), mediates platelet adhesion and induces signaling leading to integrin activation. Phosphoinositol 3-kinase (PI3K) is important in GPIb-IX–mediated signaling. PI3K–dependent signaling mechanisms, however, are unclear. We...

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Bibliografski detalji
Glavni autori: Yin, Hong, Stojanovic, Aleksandra, Hay, Nissim, Du, Xiaoping
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2008
Teme:
Hemostasis, Thrombosis, and Vascular Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200862/
https://ncbi.nlm.nih.gov/pubmed/17914025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-04-085514
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