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The role of Akt in the signaling pathway of the glycoprotein Ib-IX–induced platelet activation
The platelet von Willebrand factor (vWF) receptor, glycoprotein Ib-IX (GPIb-IX), mediates platelet adhesion and induces signaling leading to integrin activation. Phosphoinositol 3-kinase (PI3K) is important in GPIb-IX–mediated signaling. PI3K–dependent signaling mechanisms, however, are unclear. We...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200862/ https://ncbi.nlm.nih.gov/pubmed/17914025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-04-085514 |
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