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LIM kinase-1 selectively promotes glycoprotein Ib-IX–mediated TXA(2) synthesis, platelet activation, and thrombosis
Current antithrombotic drugs have an adverse effect on bleeding, highlighting the need for new molecular targets for developing antithrombotic drugs that minimally affect hemostasis. Here we show that LIMK1(−/−) mice have defective arterial thrombosis in vivo but do not differ from wild-type mice wi...
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| Hoofdauteurs: | , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668491/ https://ncbi.nlm.nih.gov/pubmed/23620575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-470765 |
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