טוען...
ADP-Stimulated Activation of Akt During Integrin Outside-in Signaling Promotes Platelet Spreading by Inhibiting Glycogen Synthase Kinase-3β
OBJECTIVE: Integrins mediate platelet adhesion and transmit “outside in” signals, leading to platelet spreading. Phosphoinositide 3-Kinases (PI3Ks) play a critical role in outside-in signaling and platelet spreading; however, the mechanisms of PI3K activation and function in outside-in signaling are...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447984/ https://ncbi.nlm.nih.gov/pubmed/22814751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.254680 |
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