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Integrin αIIb-Mediated PI3K/Akt Activation in Platelets

Integrin αIIbβ3 mediated bidirectional signaling plays a critical role in thrombosis and haemostasis. Signaling mediated by the β3 subunit has been extensively studied, but αIIb mediated signaling has not been characterized. Previously, we reported that platelet granule secretion and TxA2 production...

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Detalhes bibliográficos
Main Authors: Niu, Haixia, Chen, Xue, Gruppo, Ralph A., Li, Ding, Wang, Yanhua, Zhang, Lin, Wang, Kemin, Chai, Weiran, Sun, Yueping, Ding, Zhongren, Gartner, T. Kent, Liu, Junling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474815/
https://ncbi.nlm.nih.gov/pubmed/23082158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047356
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