Llwytho...

An important role for Akt3 in platelet activation and thrombosis

The Akt family of serine/threonine kinases includes Akt1, Akt2, and Akt3 isoforms. Prior studies have reported that Akt1 and Akt2, but not Akt3, are expressed in platelets. Here, we show that Akt3 is expressed in substantial amounts in platelets. Akt3(−/−) mouse platelets selectively exhibit impaire...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: O'Brien, Kelly A., Stojanovic-Terpo, Aleksandra, Hay, Nissim, Du, Xiaoping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204738/
https://ncbi.nlm.nih.gov/pubmed/21821713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-323204
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