Differential roles of the NADPH-oxidase 1 and 2 in platelet activation and thrombosis

OBJECTIVE: Reactive oxygen species (ROS) are known to regulate platelet activation; however, the mechanisms of ROS production during platelet activation remain unclear. Platelets express different isoforms of nicotinamide adenine dinucleotide (phosphate) (NAD(P)H) oxidases (NOXs). Here we investigat...

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Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Delaney, Michael Keegan, Kim, Kyungho, Estevez, Brian, Xu, Zheng, Stojanovic-Terpo, Aleksandra, Shen, Bo, Ushio-Fukai, Masuko, Cho, Jaehyung, Du, Xiaoping
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850088/
https://ncbi.nlm.nih.gov/pubmed/26988594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307308
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