Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA

PCNA ubiquitination in response to DNA damage leads to the recruitment of specialized translesion polymerases to the damage locus. This constitutes one of the initial steps in translesion synthesis (TLS)—a critical pathway for cell survival and for maintenance of genome stability. The recent crystal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tsutakawa, Susan E., Van Wynsberghe, Adam W., Freudenthal, Bret D., Weinacht, Christopher P., Gakhar, Lokesh, Washington, M. Todd, Zhuang, Zhihao, Tainer, John A., Ivanov, Ivaylo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203759/
https://ncbi.nlm.nih.gov/pubmed/22006297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110480108
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak