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A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions
Eukaryotic proliferating cell nuclear antigen (PCNA) is an essential replication accessory factor that interacts with a variety of proteins involved in DNA replication and repair. Each monomer of PCNA has an N-terminal domain A and a C-terminal domain B. In the structure of the wild-type PCNA protei...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685733/ https://ncbi.nlm.nih.gov/pubmed/19465770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909011329 |
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