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Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

The base excision repair (BER) pathway repairs oxidized lesions in the DNA that result from reactive oxygen species generated in cells. If left unrepaired, these damaged DNA bases can disrupt cellular processes such as replication. NEIL1 is one of the 11 human DNA glycosylases that catalyze the firs...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Prakash, Aishwarya, Moharana, Kedar, Wallace, Susan S., Doublié, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389659/
https://ncbi.nlm.nih.gov/pubmed/27994037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1282
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