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Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase
The base excision repair (BER) pathway repairs oxidized lesions in the DNA that result from reactive oxygen species generated in cells. If left unrepaired, these damaged DNA bases can disrupt cellular processes such as replication. NEIL1 is one of the 11 human DNA glycosylases that catalyze the firs...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389659/ https://ncbi.nlm.nih.gov/pubmed/27994037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1282 |
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