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Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

The base excision repair (BER) pathway repairs oxidized lesions in the DNA that result from reactive oxygen species generated in cells. If left unrepaired, these damaged DNA bases can disrupt cellular processes such as replication. NEIL1 is one of the 11 human DNA glycosylases that catalyze the firs...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Prakash, Aishwarya, Moharana, Kedar, Wallace, Susan S., Doublié, Sylvie
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389659/
https://ncbi.nlm.nih.gov/pubmed/27994037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1282
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