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Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

The base excision repair (BER) pathway repairs oxidized lesions in the DNA that result from reactive oxygen species generated in cells. If left unrepaired, these damaged DNA bases can disrupt cellular processes such as replication. NEIL1 is one of the 11 human DNA glycosylases that catalyze the firs...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Prakash, Aishwarya, Moharana, Kedar, Wallace, Susan S., Doublié, Sylvie
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389659/
https://ncbi.nlm.nih.gov/pubmed/27994037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1282
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