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Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase
The base excision repair (BER) pathway repairs oxidized lesions in the DNA that result from reactive oxygen species generated in cells. If left unrepaired, these damaged DNA bases can disrupt cellular processes such as replication. NEIL1 is one of the 11 human DNA glycosylases that catalyze the firs...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389659/ https://ncbi.nlm.nih.gov/pubmed/27994037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1282 |
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