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Genome and Cancer Single Nucleotide Polymorphisms of the Human NEIL1 DNA Glycosylase: Activity, Structure, and the Effect of Editing
The repair of free-radical oxidative DNA damage is carried out by lesion-specific DNA glycosylases as the first step of the highly conserved base excision repair (BER) pathway. In humans, three orthologs of the prototypical endonuclease VIII (Nei), the Nei-like NEIL1–3 enzymes are involved in the re...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926126/ https://ncbi.nlm.nih.gov/pubmed/24382305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.12.003 |
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