Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

The human body contains thousands of unique cell types, each with specialized functions. Cell identity is governed in large part by gene transcription programs, which are determined by regulatory elements encoded in DNA. To identify regulatory elements active in seven cell lines representative of di...

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Autors principals: Song, Lingyun, Zhang, Zhancheng, Grasfeder, Linda L., Boyle, Alan P., Giresi, Paul G., Lee, Bum-Kyu, Sheffield, Nathan C., Gräf, Stefan, Huss, Mikael, Keefe, Damian, Liu, Zheng, London, Darin, McDaniell, Ryan M., Shibata, Yoichiro, Showers, Kimberly A., Simon, Jeremy M., Vales, Teresa, Wang, Tianyuan, Winter, Deborah, Zhang, Zhuzhu, Clarke, Neil D., Birney, Ewan, Iyer, Vishwanath R., Crawford, Gregory E., Lieb, Jason D., Furey, Terrence S.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202292/
https://ncbi.nlm.nih.gov/pubmed/21750106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.121541.111
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