High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

Regulation of gene transcription in diverse cell types is determined largely by varied sets of cis-elements where transcription factors bind. Here we demonstrate that data from a single high-throughput DNase I hypersensitivity assay can delineate hundreds of thousands of base-pair resolution in vivo...

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Hlavní autoři: Boyle, Alan P., Song, Lingyun, Lee, Bum-Kyu, London, Darin, Keefe, Damian, Birney, Ewan, Iyer, Vishwanath R., Crawford, Gregory E., Furey, Terrence S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2011
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Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044859/
https://ncbi.nlm.nih.gov/pubmed/21106903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.112656.110
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