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FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin

DNA segments that actively regulate transcription in vivo are typically characterized by eviction of nucleosomes from chromatin and are experimentally identified by their hypersensitivity to nucleases. Here we demonstrate a simple procedure for the isolation of nucleosome-depleted DNA from human chr...

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Detalhes bibliográficos
Main Authors: Giresi, Paul G., Kim, Jonghwan, McDaniell, Ryan M., Iyer, Vishwanath R., Lieb, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891346/
https://ncbi.nlm.nih.gov/pubmed/17179217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5533506
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