FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin

DNA segments that actively regulate transcription in vivo are typically characterized by eviction of nucleosomes from chromatin and are experimentally identified by their hypersensitivity to nucleases. Here we demonstrate a simple procedure for the isolation of nucleosome-depleted DNA from human chr...

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Bibliographic Details
Main Authors: Giresi, Paul G., Kim, Jonghwan, McDaniell, Ryan M., Iyer, Vishwanath R., Lieb, Jason D.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Methods
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891346/
https://ncbi.nlm.nih.gov/pubmed/17179217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5533506
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