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Hydroxyurea induces de novo copy number variants in human cells
Copy number variants (CNVs) are widely distributed throughout the human genome, where they contribute to genetic variation and phenotypic diversity. Spontaneous CNVs are also a major cause of genetic and developmental disorders and arise frequently in cancer cells. As with all mutation classes, gene...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198378/ https://ncbi.nlm.nih.gov/pubmed/21987784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109272108 |
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