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Hydroxyurea induces de novo copy number variants in human cells

Copy number variants (CNVs) are widely distributed throughout the human genome, where they contribute to genetic variation and phenotypic diversity. Spontaneous CNVs are also a major cause of genetic and developmental disorders and arise frequently in cancer cells. As with all mutation classes, gene...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Arlt, Martin F., Ozdemir, Alev Cagla, Birkeland, Shanda R., Wilson, Thomas E., Glover, Thomas W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198378/
https://ncbi.nlm.nih.gov/pubmed/21987784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109272108
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