Large transcription units unify copy number variants and common fragile sites arising under replication stress

Copy number variants (CNVs) resulting from genomic deletions and duplications and common fragile sites (CFSs) seen as breaks on metaphase chromosomes are distinct forms of structural chromosome instability precipitated by replication inhibition. Although they share a common induction mechanism, it i...

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Bibliografiset tiedot
Julkaisussa:Genome Res
Päätekijät: Wilson, Thomas E., Arlt, Martin F., Park, So Hae, Rajendran, Sountharia, Paulsen, Michelle, Ljungman, Mats, Glover, Thomas W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2015
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315293/
https://ncbi.nlm.nih.gov/pubmed/25373142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.177121.114
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