Large transcription units unify copy number variants and common fragile sites arising under replication stress

Copy number variants (CNVs) resulting from genomic deletions and duplications and common fragile sites (CFSs) seen as breaks on metaphase chromosomes are distinct forms of structural chromosome instability precipitated by replication inhibition. Although they share a common induction mechanism, it i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genome Res
Hauptverfasser: Wilson, Thomas E., Arlt, Martin F., Park, So Hae, Rajendran, Sountharia, Paulsen, Michelle, Ljungman, Mats, Glover, Thomas W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315293/
https://ncbi.nlm.nih.gov/pubmed/25373142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.177121.114
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge