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Large transcription units unify copy number variants and common fragile sites arising under replication stress
Copy number variants (CNVs) resulting from genomic deletions and duplications and common fragile sites (CFSs) seen as breaks on metaphase chromosomes are distinct forms of structural chromosome instability precipitated by replication inhibition. Although they share a common induction mechanism, it i...
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| Pubblicato in: | Genome Res |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315293/ https://ncbi.nlm.nih.gov/pubmed/25373142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.177121.114 |
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