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FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection
OBJECTIVE: FUT2 encodes the α(1,2) fucosyltransferase that determines blood group secretor status. Homozygotes (A/A) for the common nonsense mutation rs601338A>G (W143X) are nonsecretors and are unable to express histo-blood group antigens in secretions and on mucosal surfaces. This mutation has...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Diabetes Association
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3198057/ https://ncbi.nlm.nih.gov/pubmed/22025780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0638 |
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