The oncoprotein p28(GANK) establishes a positive feedback loop in β-catenin signaling

p28(GANK) (also known as PSMD10 or gankyrin) is a novel oncoprotein that is highly expressed in hepatocellular carcinoma (HCC). Through its interaction with various proteins, p28(GANK) mediates the degradation of the tumor suppressor proteins Rb and p53. Although p53 was reported to downregulate β-c...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Dong, Li-wei, Yang, Guang-zhen, Pan, Yu-fei, Chen, Yao, Tan, Ye-xiong, Dai, Rong-yang, Ren, Yi-bin, Fu, Jing, Wang, Hong-yang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193485/
https://ncbi.nlm.nih.gov/pubmed/21691299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.103
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы