Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma

Oxidative stress status has a key role in hepatocellular carcinoma (HCC) development and progression. Normally, reactive oxygen species (ROS) levels are tightly controlled by an inducible antioxidant program that responds to cellular stressors. How HCC cells respond to excessive oxidative stress rem...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Yang, Chun, Tan, Ye-xiong, Yang, Guang-zhen, Zhang, Jian, Pan, Yu-fei, Liu, Chen, Fu, Jing, Chen, Yao, Ding, Zhi-wen, Dong, Li-wei, Wang, Hong-yang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854728/
https://ncbi.nlm.nih.gov/pubmed/27091842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151208
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