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Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma

Oxidative stress status has a key role in hepatocellular carcinoma (HCC) development and progression. Normally, reactive oxygen species (ROS) levels are tightly controlled by an inducible antioxidant program that responds to cellular stressors. How HCC cells respond to excessive oxidative stress rem...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Yang, Chun, Tan, Ye-xiong, Yang, Guang-zhen, Zhang, Jian, Pan, Yu-fei, Liu, Chen, Fu, Jing, Chen, Yao, Ding, Zhi-wen, Dong, Li-wei, Wang, Hong-yang
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854728/
https://ncbi.nlm.nih.gov/pubmed/27091842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151208
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